Forschung

Publikationen

2024

Necrosectomy Versus Stand-Alone Suboccipital Decompressive Craniectomy for the Management of Space-Occupying Cerebellar Infarctions-A Retrospective Multicenter Study.

Hernandez-Duran S, Walter J, Behmanesh B, Bernstock JD, Czabanka M, Dinc N, Dubinski D, Freiman TM, Günther A, Hellmuth K, Herrmann E, Konczalla J, Maier I, Melkonian R, Mielke D, Müller SJ, Naser P, Rohde V, Schaefer JH, Senft C, Storch A, Unterberg A, Walter U, Wittstock M, Gessler F, Won SY.Neurosurgery. 2024 Mar 1;94(3):559-566. doi: 10.1227/neu.0000000000002707. Epub 2023 Oct 6.PMID: 37800900

Endovascular Applications for the Management of High-Grade Gliomas in the Modern Era.

Kappel AD, Jha R, Guggilapu S, Smith WJ, Feroze AH, Dmytriw AA, Vicenty-Padilla J, Alcedo Guardia RE, Gessler FA, Patel NJ, Du R, See AP, Peruzzi PP, Aziz-Sultan MA, Bernstock JD.Cancers (Basel). 2024 Apr 22;16(8):1594. doi: 10.3390/cancers16081594.PMID: 38672676 

Functional Outcomes in Conservatively vs Surgically Treated Cerebellar Infarcts.

Won SY, Hernández-Durán S, Behmanesh B, Bernstock JD, Czabanka M, Dinc N, Dubinski D, Freiman TM, Günther A, Hellmuth K, Herrmann E, Konczalla J, Maier I, Melkonian R, Mielke D, Naser P, Rohde V, Senft C, Storch A, Unterberg A, Walter J, Walter U, Wittstock M, Schaefer JH, Gessler F.JAMA Neurol. 2024 Feb 26;81(4):384-93. doi: 10.1001/jamaneurol.2023.5773. Online ahead of print.PMID: 38407889

Leveraging artificial intelligence in neurosurgery-unveiling ChatGPT for neurosurgical discharge summaries and operative reports.

Dubinski D, Won SY, Trnovec S, Behmanesh B, Baumgarten P, Dinc N, Konczalla J, Chan A, Bernstock JD, Freiman TM, Gessler F.Acta Neurochir (Wien). 2024 Jan 26;166(1):38. doi: 10.1007/s00701-024-05908-3.PMID: 38277081 

From the Oral Cavity to the Spine: Prevalence of Oral Cavity Infections in Patients with Pyogenic Spinal Infection.

Kilinc F, Gessler F, Kessel J, Dubinski D, Won SY, Tanneberger A, Ghanaati S, Prinz V, Czabanka M, Setzer M, Freiman T, Behmanesh B.J Clin Med. 2024 Feb 11;13(4):1040. doi: 10.3390/jcm13041040.PMID: 38398352 

Red blood cell transfusion in patients undergoing elective primary glioblastoma resection.

Neef V, König S, Becker H, Dubinski D, Flinspach A, Raimann FJ, Weber K, Ronellenfitsch MW, Konczalla J, Hattingen E, Czabanka M, Senft C, Zacharowski K, Baumgarten P.Blood Transfus. 2024 Jan 11. doi: 10.2450/BloodTransfus.613. Online ahead of print.PMID: 38315541 

An anti-PF4 antibody-related disorder with cerebral venous sinus thrombosis and thrombocytopenia initially presenting as intracranial hemorrhage.

Wittstock M, Cantré D, Won SY, Jürs AV, Wesche J, Greger N, Greinacher A, Thiele T.J Neurol. 2024 Apr 10. doi: 10.1007/s00415-024-12373-6. Online ahead of print.PMID: 38597942 

Efficacy and safety of bedside percutaneous three-millimeter twist-drill trephination under local anesthesia-a retrospective study of 1000 patients.

Puhahn-Schmeiser B, Wegent H, Won SY, Zentner J, Freiman TM.Acta Neurochir (Wien). 2024 Feb 17;166(1):87. doi: 10.1007/s00701-024-05958-7.PMID: 38366108

Bilateral Foramina Parietalia Permagna - A Calvarial Defect Caused by Haploinsufficiency of the Msh Homeobox 2 Gene: A Case Report and Current Literature Review.

Kahl N, Lüsebrink N, Schubert-Bast S, Freiman TM, Kieslich M.Neuropediatrics. 2024 Mar 6. doi: 10.1055/s-0044-1781465. Online ahead of print.PMID: 38447947 

Estimation of prognosis in patients after decompressive craniectomy after malignant hemispheric infarction: multifactorial scoring scale.

Chrenko R, Trnovec S, Hanko M, Kolejak K, Liska M, Nedomova B.Bratisl Lek Listy. 2024;125(5):305-310. doi: 10.4149/BLL_2024_45.PMID: 38624055

2023

SUMOtherapeutics for Ischemic Stroke.

Karandikar P, Gerstl JVE, Kappel AD, Won SY, Dubinski D, Garcia-Segura ME, Gessler FA, See AP, Peruzzotti-Jametti L, Bernstock JD.Pharmaceuticals (Basel). 2023 Apr 29;16(5):673. doi: 10.3390/ph16050673.PMID: 37242456 

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.

National Institute for Health and Care Research Global Health Research Unit on Global Surgery.Br J Surg. 2023 Jun 12;110(7):804-817. doi: 10.1093/bjs/znad092.PMID: 37079880 

Positioning SUMO as an immunological facilitator of oncolytic viruses for high-grade glioma.

Karandikar PV, Suh L, Gerstl JVE, Blitz SE, Qu QR, Won SY, Gessler FA, Arnaout O, Smith TR, Peruzzi PP, Yang W, Friedman GK, Bernstock JD.Front Cell Dev Biol. 2023 Oct 4;11:1271575. doi: 10.3389/fcell.2023.1271575. eCollection 2023.PMID: 37860820 Free

Cerebellar Stroke Score and Grading Scale for the Prediction of Mortality and Outcomes in Ischemic Cerebellar Stroke.

Won SY, Melkonian R, Behmanesh B, Bernstock JD, Czabanka M, Dubinski D, Freiman TM, Günther A, Hellmuth K, Hernandez-Duran S, Herrmann E, Konczalla J, Maier I, Mielke D, Naser P, Rohde V, Schaefer JH, Senft C, Storch A, Trnovec S, Unterberg A, Walter J, Walter U, Wittstock M, Dinc N, Gessler F.Stroke. 2023 Oct;54(10):2569-2575. doi: 10.1161/STROKEAHA.123.043478. Epub 2023 Aug 8.PMID: 37551591

Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance.

Bernstock JD, Willis CM, Garcia-Segura ME, Gaude E, Anni D, Lee YJ, Thomas LW, Casey A, Vicario N, Leonardi T, Nicaise AM, Gessler FA, Izzy S, Buffelli MR, Seidlitz J, Srinivasan S, Murphy MP, Ashcroft M, Cambiaghi M, Hallenbeck JM, Peruzzotti-Jametti L.bioRxiv [Preprint]. 2023 Mar 30:2023.03.29.534718. doi: 10.1101/2023.03.29.534718.PMID: 37205496 

Necrosectomy Versus Stand-Alone Suboccipital Decompressive Craniectomy for the Management of Space-Occupying Cerebellar Infarctions-A Retrospective Multicenter Study.

Hernandez-Duran S, Walter J, Behmanesh B, Bernstock JD, Czabanka M, Dinc N, Dubinski D, Freiman TM, Günther A, Hellmuth K, Herrmann E, Konczalla J, Maier I, Melkonian R, Mielke D, Müller SJ, Naser P, Rohde V, Schaefer JH, Senft C, Storch A, Unterberg A, Walter U, Wittstock M, Gessler F, Won SY.Neurosurgery. 2024 Mar 1;94(3):559-566. doi: 10.1227/neu.0000000000002707. Epub 2023 Oct 6.PMID: 37800900

Frailty in cerebellar ischemic stroke-The significance of temporal muscle thickness.

Dubinski D, Won SY, Mattes I, Trnovec S, Behmanesh B, Cantré D, Baumgarten P, Dinc N, Konczalla J, Wittstock M, Freiman TM, Gessler F.Front Neurol. 2023 Sep 26;14:1193685. doi: 10.3389/fneur.2023.1193685. eCollection 2023.PMID: 37822528 

Frailty in Traumatic Brain Injury-The Significance of Temporal Muscle Thickness.

Dubinski D, Won SY, Meyer-Wilmes J, Trnovec S, Rafaelian A, Behmanesh B, Cantré D, Baumgarten P, Dinc N, Konczalla J, Wittstock M, Bernstock JD, Freiman TM, Gessler F.J Clin Med. 2023 Dec 11;12(24):7625. doi: 10.3390/jcm12247625.PMID: 38137693 

Safety and feasibility of outpatient parenteral antimicrobial therapy for patients with spinal infection.

Kilinc F, Setzer M, Behmanesh B, Jussen D, Gessler F, Keil F, Kempf VAJ, Kessel J, Czabanka M, Prinz V.Sci Rep. 2023 Apr 26;13(1):6863. doi: 10.1038/s41598-023-33502-7.PMID: 37100824 

Effectiveness of outpatient parenteral antimicrobial therapy (OPAT) for patients with cranial infection.

Kilinc F, Setzer M, Behmanesh B, Jussen D, Gessler F, Bayerl S, Kempf VAJ, Kessel J, Czabanka M, Prinz V.Front Med (Lausanne). 2023 Oct 24;10:1202969. doi: 10.3389/fmed.2023.1202969. eCollection 2023.PMID: 37942421 

Blood Clots May Compromise Intracranial Pressure Measurement Using Air-Pouch Intracranial Pressure Probes.

Won SY, Herrmann S, Dubinski D, Behmanesh B, Trnovec S, Dinc N, Bernstock JD, Freiman TM, Gessler FA.J Clin Med. 2023 May 25;12(11):3661. doi: 10.3390/jcm12113661.PMID: 37297856 

Surgical management and clinical outcome of cervical, thoracic and thoracolumbar spinal tuberculosis in a middle-European adult population.

Kilinc F, Setzer M, Behmanesh B, Jussen D, Geßler F, Prinz V, Czabanka M.Sci Rep. 2023 Apr 28;13(1):7000. doi: 10.1038/s41598-023-34178-9.PMID: 37117321 

The Long-Term Use of Diagnostic Subdural Electroencephalogram Electrodes and Subdural Hematoma: A Prospective Cohort Study.

Won SY, Freiman TM, Lee-Müller SS, Dubinski D, Willems LM, Reif PS, Hattingen E, Ullmann J, Herrmann E, Melzer N, Seifert V, Gessler F, Rosenow F, Konczalla J, Strzelczyk A.Crit Care Med. 2023 Dec 1;51(12):1754-1765. doi: 10.1097/CCM.0000000000006033. Epub 2023 Aug 28.PMID: 37638780

Retrospective comparison of long-term functionality and revision rate of two different shunt valves in pediatric and adult patients.

Busse LC, Dubinski D, Gessler F, Dinc N, Konczalla J, Czabanka M, Senft C, Freiman TM, Baumgarten P.Acta Neurochir (Wien). 2023 Sep;165(9):2541-2549. doi: 10.1007/s00701-023-05719-y. Epub 2023 Aug 2.PMID: 37528210 

Reappraisal of Intracerebral Hemorrhages and Intracerebral Hemorrhage Grading Scale Score in Surgically and Medically Managed Cerebellar Intracerebral Hemorrhage.

Won SY, Walter J, Hernandez-Duran S, Alhalabi OT, Behmanesh B, Bernstock JD, Czabanka M, Dinc N, Dubinski D, Flüh C, Freiman TM, Grosch AS, Herrmann E, Kang YS, Konczalla J, Kramer A, Lehmann F, Lemcke J, Melkonian R, Mielke D, Müller L, Ringel F, Rohde V, Schneider M, Senft C, Schuss P, Turgut MÖ, Synowitz M, Ullmann JM, Vatter H, Zweckberger K, Kilinc F, Gessler F.Neurosurgery. 2023 May 1;92(5):1021-1028. doi: 10.1227/neu.0000000000002318. Epub 2022 Dec 21.PMID: 36700686

Quality of Life Following Surgical and Conservative Therapy of Pyogenic Spinal Infection: A Study of Long-term Outcome in 210 Patients.

Behmanesh B, Gessler F, Duetzmann S, Seifert V, Weise L, Setzer M.J Neurol Surg A Cent Eur Neurosurg. 2023 Jan;84(1):14-20. doi: 10.1055/s-0041-1722965. Epub 2021 Mar 9.PMID: 33690878

2022

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.

COVIDSurg Collaborative; GlobalSurg Collaborative.Anaesthesia. 2022 Jan;77(1):28-39. doi: 10.1111/anae.15563. Epub 2021 Aug 24.PMID: 34428858 

Immunotherapy approaches for the treatment of diffuse midline gliomas.

Bernstock JD, Hoffman SE, Kappel AD, Valdes PA, Essayed W, Klinger NV, Kang KD, Totsch SK, Olsen HE, Schlappi CW, Filipski K, Gessler FA, Baird L, Filbin MG, Hashizume R, Becher OJ, Friedman GK.Oncoimmunology. 2022 Sep 26;11(1):2124058. doi: 10.1080/2162402X.2022.2124058. eCollection 2022.PMID: 36185807 

Neurogenic Dysphagia in Subdural Hematoma.

Won SY, Krieger S, Dubinski D, Gessler F, Behmanesh B, Freiman TM, Konczalla J, Seifert V, Lapa S.Front Neurol. 2022 Jan 26;12:701378. doi: 10.3389/fneur.2021.701378. eCollection 2021.PMID: 35153966 

Standard clinical approaches and emerging modalities for glioblastoma imaging.

Bernstock JD, Gary SE, Klinger N, Valdes PA, Ibn Essayed W, Olsen HE, Chagoya G, Elsayed G, Yamashita D, Schuss P, Gessler FA, Paolo Peruzzi P, Bag AK, Friedman GK.Neurooncol Adv. 2022 May 26;4(1):vdac080. doi: 10.1093/noajnl/vdac080. eCollection 2022 Jan-Dec.PMID: 35821676 

Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword.

Blitz SE, Kappel AD, Gessler FA, Klinger NV, Arnaout O, Lu Y, Peruzzi PP, Smith TR, Chiocca EA, Friedman GK, Bernstock JD.Int J Mol Sci. 2022 Feb 4;23(3):1808. doi: 10.3390/ijms23031808.PMID: 35163730 

Intracranial pressure monitoring in posterior fossa lesions-systematic review and meta-analysis.

Won SY, Dubinski D, Hagemeier J, Behmanesh B, Trnovec S, Bernstock JD, Freiman TM, Gessler F.Neurosurg Rev. 2022 Jun;45(3):1933-1939. doi: 10.1007/s10143-022-01746-y. Epub 2022 Feb 3.PMID: 35118578

Treatment-Limiting Decisions in Patients with Spontaneous Intracerebral Hemorrhage.

Lehmann F, Schneider M, Bernstock JD, Bode C, Borger V, Ehrentraut SF, Gessler F, Potthoff AL, Putensen C, Schenk LM, Zimmermann J, Vatter H, Schuss P, Hadjiathanasiou A.Medicina (Kaunas). 2022 Jul 25;58(8):989. doi: 10.3390/medicina58080989.PMID: 35893103 

Significance of Temporal Muscle Thickness in Chronic Subdural Hematoma.

Dubinski D, Won SY, Behmanesh B, Cantré D, Mattes I, Trnovec S, Baumgarten P, Schuss P, Freiman TM, Gessler F.J Clin Med. 2022 Oct 31;11(21):6456. doi: 10.3390/jcm11216456.PMID: 36362682 

Recurrence of chronic subdural hematoma due to low-grade infection.

Dubinski D, Won SY, Trnovec S, Gounko K, Baumgarten P, Warnke P, Cantré D, Behmanesh B, Bernstock JD, Freiman TM, Gessler F, Sola S.Front Neurol. 2022 Sep 23;13:1012255. doi: 10.3389/fneur.2022.1012255. eCollection 2022.PMID: 36212639 

Therapeutic Anticoagulation Impacts MR Morphologic Recurrence Patterns in Glioblastoma-A Matched-Pair Analysis.

Dubinski D, Won SY, Behmanesh B, Dosch M, Puchinin V, Baumgarten P, Bernstock JD, Voss M, Schuss P, Konczalla J, Czabanka M, Freiman TM, Gessler F.J Clin Med. 2022 Jan 14;11(2):422. doi: 10.3390/jcm11020422.PMID: 35054114 

Acute-on-chronic subdural hematoma: a new entity for prophylactic anti-epileptic treatment?

Won SY, Dubinski D, Freiman T, Seifert V, Gessler F, Strzelczyk A, Konczalla J.Eur J Trauma Emerg Surg. 2022 Apr;48(2):933-942. doi: 10.1007/s00068-020-01508-9. Epub 2020 Sep 28.PMID: 32986132 

Accuracy of Robotic and Frame-Based Stereotactic Neurosurgery in a Phantom Model.

Spyrantis A, Woebbecke T, Rueß D, Constantinescu A, Gierich A, Luyken K, Visser-Vandewalle V, Herrmann E, Gessler F, Czabanka M, Treuer H, Ruge M, Freiman TM.Front Neurorobot. 2022 Mar 25;16:762317. doi: 10.3389/fnbot.2022.762317. eCollection 2022.PMID: 35515711 

Incidence, risk factors and clinical course of pyogenic spondylodiscitis patients with pulmonary embolism.

Dubinski D, Won SY, Keil F, Behmanesh B, Dosch M, Baumgarten P, Bernstock JD, Seifert V, Freiman TM, Gessler F.Eur J Trauma Emerg Surg. 2022 Jun;48(3):2229-2236. doi: 10.1007/s00068-021-01776-z. Epub 2021 Sep 2.PMID: 34476510 

Direct oral anticoagulants vs. low-molecular-weight heparin for pulmonary embolism in patients with glioblastoma.

Dubinski D, Won SY, Voss M, Keil F, Miesbach W, Behmanesh B, Dosch M, Baumgarten P, Bernstock JD, Seifert V, Freiman TM, Gessler F.Neurosurg Rev. 2022 Feb;45(1):451-457. doi: 10.1007/s10143-021-01539-9. Epub 2021 Apr 26.PMID: 33900495 

Reappraisal of Intracerebral Hemorrhages and Intracerebral Hemorrhage Grading Scale Score in Surgically and Medically Managed Cerebellar Intracerebral Hemorrhage.

Won SY, Walter J, Hernandez-Duran S, Alhalabi OT, Behmanesh B, Bernstock JD, Czabanka M, Dinc N, Dubinski D, Flüh C, Freiman TM, Grosch AS, Herrmann E, Kang YS, Konczalla J, Kramer A, Lehmann F, Lemcke J, Melkonian R, Mielke D, Müller L, Ringel F, Rohde V, Schneider M, Senft C, Schuss P, Turgut MÖ, Synowitz M, Ullmann JM, Vatter H, Zweckberger K, Kilinc F, Gessler F.Neurosurgery. 2023 May 1;92(5):1021-1028. doi: 10.1227/neu.0000000000002318. Epub 2022 Dec 21.PMID: 36700686

2021

Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study.

COVIDSurg Collaborative; GlobalSurg Collaborative.Anaesthesia. 2021 Jun;76(6):748-758. doi: 10.1111/anae.15458. Epub 2021 Mar 9.PMID: 33690889 

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

COVIDSurg Collaborative, GlobalSurg Collaborative.Br J Surg. 2021 Sep 27;108(9):1056-1063. doi: 10.1093/bjs/znab101.PMID: 33761533 

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.

COVIDSurg Collaborative; GlobalSurg Collaborative.Anaesthesia. 2022 Jan;77(1):28-39. doi: 10.1111/anae.15563. Epub 2021 Aug 24.PMID: 34428858 

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.

COVIDSurg Collaborative; GlobalSurg Collaborative.Anaesthesia. 2021 Nov;76(11):1454-1464. doi: 10.1111/anae.15560. Epub 2021 Aug 9.PMID: 34371522 

Neurogenic Dysphagia in Subdural Hematoma.

Won SY, Krieger S, Dubinski D, Gessler F, Behmanesh B, Freiman TM, Konczalla J, Seifert V, Lapa S.Front Neurol. 2022 Jan 26;12:701378. doi: 10.3389/fneur.2021.701378. eCollection 2021.PMID: 35153966 

Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery.

Behmanesh B, Gessler F, Adam E, Strouhal U, Won SY, Dubinski D, Seifert V, Konczalla J, Senft C.J Clin Med. 2021 Dec 7;10(24):5734. doi: 10.3390/jcm10245734.PMID: 34945029 

Incidence, risk factors and clinical course of pyogenic spondylodiscitis patients with pulmonary embolism.

Dubinski D, Won SY, Keil F, Behmanesh B, Dosch M, Baumgarten P, Bernstock JD, Seifert V, Freiman TM, Gessler F.Eur J Trauma Emerg Surg. 2022 Jun;48(3):2229-2236. doi: 10.1007/s00068-021-01776-z. Epub 2021 Sep 2.PMID: 34476510 

Direct oral anticoagulants vs. low-molecular-weight heparin for pulmonary embolism in patients with glioblastoma.

Dubinski D, Won SY, Voss M, Keil F, Miesbach W, Behmanesh B, Dosch M, Baumgarten P, Bernstock JD, Seifert V, Freiman TM, Gessler F.Neurosurg Rev. 2022 Feb;45(1):451-457. doi: 10.1007/s10143-021-01539-9. Epub 2021 Apr 26.PMID: 33900495 

Short- and Long-Term Effects of Rehabilitation after Perimesencephalic Subarachnoid Hemorrhage.

Schmitz J, Kashefiolasl S, Brawanski N, Dinc N, Gessler F, Senft C, Tritt S, Seifert V, Konczalla J.Diseases. 2021 Oct 7;9(4):69. doi: 10.3390/diseases9040069.PMID: 34698166 

Admission Dehydration Status Portends Adverse Short-Term Mortality in Patients with Spontaneous Intracerebral Hemorrhage.

Lehmann F, Schenk LM, Bernstock JD, Bode C, Borger V, Gessler F, Güresir E, Hamed M, Potthoff AL, Putensen C, Schneider M, Zimmermann J, Vatter H, Schuss P, Hadjiathanasiou A.J Clin Med. 2021 Dec 17;10(24):5939. doi: 10.3390/jcm10245939.PMID: 34945232 

Aberrant hippocampal mossy fibers in temporal lobe epilepsy target excitatory and inhibitory neurons.

Puhahn-Schmeiser B, Leicht K, Gessler F, Freiman TM.Epilepsia. 2021 Oct;62(10):2539-2550. doi: 10.1111/epi.17035. Epub 2021 Aug 28.PMID: 34453315

The Added Value of Cerebral Imaging in Patients With Pyogenic Spinal Infection.

Behmanesh B, Gessler F, Kessel J, Keil F, Seifert V, Bruder M, Setzer M.Front Neurol. 2021 May 4;12:628256. doi: 10.3389/fneur.2021.628256. eCollection 2021.PMID: 34017299 

Neurosurgical Considerations Regarding Decompressive Craniectomy for Intracerebral Hemorrhage after SARS-CoV-2-Vaccination in Vaccine Induced Thrombotic Thrombocytopenia-VITT.

Gessler F, Schmitz AK, Dubinski D, Bernstock JD, Lehmann F, Won SY, Wittstock M, Güresir E, Hadjiathanasiou A, Zimmermann J, Miesbach W, Freiman T, Vatter H, Schuss P.J Clin Med. 2021 Jun 24;10(13):2777. doi: 10.3390/jcm10132777.PMID: 34202817 

Predictive Relevance of Baseline Lactate and Glucose Levels in Patients with Spontaneous Deep-Seated Intracerebral Hemorrhage.

Lehmann F, Schenk LM, Schneider M, Bernstock JD, Bode C, Borger V, Gessler F, Güresir E, Hadjiathanasiou A, Hamed M, Müller M, Putensen C, Zimmermann J, Vatter H, Schuss P.Brain Sci. 2021 May 14;11(5):633. doi: 10.3390/brainsci11050633.PMID: 34069048 

Quality of Life Following Surgical and Conservative Therapy of Pyogenic Spinal Infection: A Study of Long-term Outcome in 210 Patients.

Behmanesh B, Gessler F, Duetzmann S, Seifert V, Weise L, Setzer M.J Neurol Surg A Cent Eur Neurosurg. 2023 Jan;84(1):14-20. doi: 10.1055/s-0041-1722965. Epub 2021 Mar 9.PMID: 33690878

Early and Late Postoperative Seizures in Meningioma Patients and Prediction by a Recent Scoring System.

Baumgarten P, Sarlak M, Monden D, Spyrantis A, Bernatz S, Gessler F, Dubinski D, Hattingen E, Marquardt G, Strzelczyk A, Rosenow F, Harter PN, Seifert V, Freiman TM.Cancers (Basel). 2021 Jan 25;13(3):450. doi: 10.3390/cancers13030450.PMID: 33504023 Free PMC article.

Supervised Valsalva Maneuver after Burr Hole Evacuation of Chronic Subdural Hematomas: A Prospective Cohort Study.

Won SY, Dubinski D, Behmanesh B, Bernstock JD, Keil F, Freiman T, Konczalla J, Seifert V, Gessler F.J Neurotrauma. 2021 Apr 1;38(7):911-917. doi: 10.1089/neu.2020.7391. Epub 2020 Dec 14.PMID: 33081586 Clinical Trial.

Triage and Allocation of Neurocritical Care Resources During the COVID 19 Pandemic - A National Survey.

Gessler F, Lehmann F, Bösel J, Fuhrer H, Neugebauer H, Wartenberg KE, Wolf S, Bernstock JD, Niesen WD, Schuss P.Front Neurol. 2021 Jan 6;11:609227. doi: 10.3389/fneur.2020.609227. eCollection 2020.PMID: 33584507 

Meningioma Surgery in Patients ≥70 Years of Age: Clinical Outcome and Validation of the SKALE Score.

Monden D, Raimann FJ, Neef V, Dubinski D, Gessler F, Keil F, Forster MT, Ronellenfitsch MW, Harter PN, Freiman TM, Hattingen E, Seifert V, Senft C, Baumgarten P.J Clin Med. 2021 Apr 22;10(9):1820. doi: 10.3390/jcm10091820.PMID: 33922009 

External validation and modification of the Oslo grading system for prediction of postoperative recurrence of chronic subdural hematoma.

Won SY, Dubinski D, Eibach M, Gessler F, Herrmann E, Keil F, Seifert V, Konczalla J, Behmanesh B.Neurosurg Rev. 2021 Apr;44(2):961-970. doi: 10.1007/s10143-020-01271-w. Epub 2020 Feb 28.PMID: 32112162

Implementation, relevance, and virtual adaptation of neuro-oncological tumor boards during the COVID-19 pandemic: a nationwide provider survey.

Schäfer N, Bumes E, Eberle F, Fox V, Gessler F, Giordano FA, Konczalla J, Onken J, Ottenhausen M, Scherer M, Schneider M, Vatter H, Herrlinger U, Schuss P.J Neurooncol. 2021 Jul;153(3):479-485. doi: 10.1007/s11060-021-03784-w. Epub 2021 Jun 11.PMID: 34115248 

Association of Isocitrate Dehydrogenase (IDH) Status With Edema to Tumor Ratio and Its Correlation With Immune Infiltration in Glioblastoma.

Dubinski D, Won SY, Rauch M, Behmanesh B, Ngassam LDC, Baumgarten P, Senft C, Harter PN, Bernstock JD, Freiman TM, Seifert V, Gessler F.Front Immunol. 2021 Mar 25;12:627650. doi: 10.3389/fimmu.2021.627650. eCollection 2021.PMID: 33868245 

Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients.

Bernatz S, Monden D, Gessler F, Radic T, Hattingen E, Senft C, Seifert V, Ronellenfitsch MW, Plate KH, Harter PN, Baumgarten P.J Mol Histol. 2021 Apr;52(2):233-243. doi: 10.1007/s10735-020-09940-2. Epub 2021 Feb 2.PMID: 33528717 

Elevated Red Cell Distribution Width to Platelet Ratio Is Associated With Poor Prognosis in Patients With Spontaneous, Deep-Seated Intracerebral Hemorrhage.

Lehmann F, Schenk LM, Bernstock JD, Bode C, Borger V, Gessler FA, Güresir E, Hamed M, Potthoff AL, Putensen C, Schneider M, Zimmermann J, Vatter H, Schuss P, Hadjiathanasiou A.Front Neurol. 2021 Nov 15;12:751510. doi: 10.3389/fneur.2021.751510. eCollection 2021.PMID: 34867736 

2020

 The Role of SUMOylation and Ubiquitination in Brain Ischaemia: Critical Concepts and Clinical Implications.

Bernstock JD, Ye DG, Estevez D, Chagoya G, Wang YC, Gessler F, Hallenbeck JM, Yang W.Curr Issues Mol Biol. 2020;35:127-144. doi: 10.21775/cimb.035.127. Epub 2019 Aug 18.PMID: 31422937 

Acute-on-chronic subdural hematoma: a new entity for prophylactic anti-epileptic treatment?

Won SY, Dubinski D, Freiman T, Seifert V, Gessler F, Strzelczyk A, Konczalla J.Eur J Trauma Emerg Surg. 2022 Apr;48(2):933-942. doi: 10.1007/s00068-020-01508-9. Epub 2020 Sep 28.PMID: 32986132 

Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice.

Bernstock JD, Vicario N, Li R, Nan L, Totsch SK, Schlappi C, Gessler F, Han X, Parenti R, Beierle EA, Whitley RJ, Aban I, Gillespie GY, Markert JM, Friedman GK.Cancer Gene Ther. 2020 Apr;27(3-4):246-255. doi: 10.1038/s41417-019-0091-0. Epub 2019 Mar 28.PMID: 30918335 

Direct oral anticoagulants for therapeutic anticoagulation in postoperative pulmonary embolism after meningioma resection.

Dubinski D, Won SY, Miesbach W, Keil F, Behmanesh B, Baumgarten P, Raimann FJ, Bernstock JD, Senft C, Seifert V, Freiman TM, Gessler F.J Clin Neurosci. 2020 Nov;81:265-269. doi: 10.1016/j.jocn.2020.09.059. Epub 2020 Oct 16.PMID: 33222927

Supervised Valsalva Maneuver after Burr Hole Evacuation of Chronic Subdural Hematomas: A Prospective Cohort Study.

Won SY, Dubinski D, Behmanesh B, Bernstock JD, Keil F, Freiman T, Konczalla J, Seifert V, Gessler F.J Neurotrauma. 2021 Apr 1;38(7):911-917. doi: 10.1089/neu.2020.7391. Epub 2020 Dec 14.PMID: 33081586 Clinical Trial.

Triage and Allocation of Neurocritical Care Resources During the COVID 19 Pandemic - A National Survey.

Gessler F, Lehmann F, Bösel J, Fuhrer H, Neugebauer H, Wartenberg KE, Wolf S, Bernstock JD, Niesen WD, Schuss P.Front Neurol. 2021 Jan 6;11:609227. doi: 10.3389/fneur.2020.609227. eCollection 2020.PMID: 33584507 

Microsurgical Treatment and Follow-Up of KOOS Grade IV Vestibular Schwannoma: Therapeutic Concept and Future Perspective.

Won SY, Kilian A, Dubinski D, Gessler F, Dinc N, Lauer M, Wolff R, Freiman T, Senft C, Konczalla J, Forster MT, Seifert V.Front Oncol. 2020 Nov 20;10:605137. doi: 10.3389/fonc.2020.605137. eCollection 2020.PMID: 33330107 

External validation and modification of the Oslo grading system for prediction of postoperative recurrence of chronic subdural hematoma.

Won SY, Dubinski D, Eibach M, Gessler F, Herrmann E, Keil F, Seifert V, Konczalla J, Behmanesh B.Neurosurg Rev. 2021 Apr;44(2):961-970. doi: 10.1007/s10143-020-01271-w. Epub 2020 Feb 28.PMID: 32112162

Pre- and Post-Surgical Dysphagia in Adults with Tumors of the Posterior Fossa: A Prospective Blinded Study.

Lapa S, Quick-Weller J, Nasari C, Dziewas R, Gessler F, Wagner M, Warnecke T, Hattingen E, Seifert V, Konczalla J.Cancers (Basel). 2020 Sep 9;12(9):2561. doi: 10.3390/cancers12092561.PMID: 32916787 

Early versus Delayed Surgery for Spinal Epidural Abscess : Clinical Outcome and Health-Related Quality of Life.

Behmanesh B, Gessler F, Quick-Weller J, Dubinski D, Konczalla J, Seifert V, Setzer M, Weise L.J Korean Neurosurg Soc. 2020 Nov;63(6):757-766. doi: 10.3340/jkns.2019.0230. Epub 2020 Aug 7.PMID: 32759625 

Impact of Comorbidities and Frailty on Early Shunt Failure in Geriatric Patients With Normal Pressure Hydrocephalus.

Hadjiathanasiou A, Kilinc F, Behmanesh B, Bernstock J, Güresir E, Heimann M, Konczalla J, Scharnböck E, Schneider M, Weinhold L, Seifert V, Vatter H, Gessler F, Schuss P.Front Med (Lausanne). 2020 Nov 30;7:596270. doi: 10.3389/fmed.2020.596270. eCollection 2020.PMID: 33330560 

Design and Rationale for First-in-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors.

Bernstock JD, Bag AK, Fiveash J, Kachurak K, Elsayed G, Chagoya G, Gessler F, Valdes PA, Madan-Swain A, Whitley R, Markert JM, Gillespie GY, Johnston JM, Friedman GK.Hum Gene Ther. 2020 Oct;31(19-20):1132-1139. doi: 10.1089/hum.2020.101. Epub 2020 Aug 17.PMID: 32657154 

Management of hydrocephalus after resection of posterior fossa lesions in pediatric and adult patients-predictors for development of hydrocephalus.

Won SY, Dubinski D, Behmanesh B, Bernstock JD, Seifert V, Konczalla J, Tritt S, Senft C, Gessler F.Neurosurg Rev. 2020 Aug;43(4):1143-1150. doi: 10.1007/s10143-019-01139-8. Epub 2019 Jul 9.PMID: 31286305

First clinical experience with the new noninvasive transfontanelle ICP monitoring device in management of children with premature IVH.

Behmanesh B, Gessler F, Dubinski D, Quick-Weller J, Cattani A, Schubert-Bast S, Seifert V, Konczalla J, Freiman TM.Neurosurg Rev. 2020 Apr;43(2):681-685. doi: 10.1007/s10143-019-01105-4. Epub 2019 May 11.PMID: 31079320

Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma.

Behmanesh B, Gessler F, Won SY, Dubinski D, Quick-Weller J, Imoehl L, Seifert V, Marquardt G.Sci Rep. 2020 Feb 11;10(1):2335. doi: 10.1038/s41598-020-59328-1.PMID: 32047239 

Surgery for Diffuse WHO Grade II Gliomas: Volumetric Analysis of a Multicenter Retrospective Cohort From the German Study Group for Intraoperative Magnetic Resonance Imaging.

Scherer M, Ahmeti H, Roder C, Gessler F, Jungk C, Pala A, Mayer B, Senft C, Tatagiba M, Synowitz M, Wirtz CR, Unterberg AW, Coburger J.Neurosurgery. 2020 Jan 1;86(1):E64-E74. doi: 10.1093/neuros/nyz397.PMID: 31574147